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Bupropion Hydrochloride 300mg

Brand Name: Wellbutrin XL®

Information on Bupropion Hydrochloride

Overview

Bupropion is an antidepressant medication used to treat major depressive disorder and seasonal affective disorder. The Zyban brand of bupropion is used to help people stop smoking by reducing cravings and other withdrawal effects.

Other strengths for generic Wellbutrin XL: 150mg, 300mg

Generic Bupropion Hydrochloride 300mg
Starter
0.0683BTC
0.0023/pill
$77.22*
$2.57/pill*
Value
0.1682BTC
0.0017/pill
$190.08*
$1.90/pill*
Super Saver
0.5411BTC
0.0014/pill
$611.58*
$1.53/pill*

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The pharmacy dispenses the product displayed. In the case of a product shortage, the pharmacy may substitute with an alternative generic.

Other Known Brand Names for Wellbutrin XL

  • Budeprion SR (US Generic Manufacturer)
  • Budeprion XL (US Generic Manufacturer)
  • Bupron SR (Sun Pharmaceutical Industries Ltd.)
  • Bupron XL (Sun Pharmaceutical Industries Ltd.)
  • UK-Bupropion SR (UK Generic mft.)
  • US-Bupropion (US Generic Manufacturer)
  • Wellbutrin (GlaxoSmithKline)
  • Wellbutrin SR (GlaxoSmithKline)
  • Wellbutrin XL (GlaxoSmithKline)
  • Zyban (GlaxoSmithKline)
  • Bupep SR
  • Bupropion Hydrochloride
  • Smoquit SR
  • Unidep SR

Usage

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Too much of this medicine can increase your risk of a seizure.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

If you take bupropion to help you stop smoking, you may continue to smoke for about 1 week after you start the medicine. Set a date to quit smoking during the second week of treatment. Talk to your doctor if you are having trouble quitting after you have used bupropion for at least 7 weeks.

Your doctor may prescribe nicotine patches or gum to help support your smoking cessation treatment. Read all directions and safety information for the nicotine product. Do not smoke at any time if you are using a nicotine product along with bupropion. Too much nicotine can cause serious side effects.

Do not stop using bupropion suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using bupropion.

This medication can cause you to have a false positive drug screening test. If you provide a urine sample for drug screening, tell the laboratory staff that you are taking bupropion.

Store at room temperature away from moisture and heat.

Dosage

Usual Adult Dose for Depression

Immediate release tablets:

Initial dose: 100 mg orally twice a day.

Maintenance dose: The dosage may be increased in 75 to 100 mg/day increments not more often than every 3 days up to the usual maintenance dose of 100 mg orally 3 times a day. The maximum dose is 450 mg/day, given in 4 divided doses; bupropion should be discontinued if there is not an adequate response to this dose. Single doses should not exceed 150 mg.

Sustained release tablets:

Initial dose: 150 mg orally once a day in the morning.

Maintenance dose: After at least 4 days, the dose may be increased to 100 to 150 mg twice a day. If there is not adequate improvement after several weeks, the dose may be increased to a maximum of 200 mg twice a day.

Extended release tablets (Wellbutrin XL):

Initial dose: 150 mg orally once a day in the morning.

Maintenance dose: After at least 4 days, the dose may be increased to 300 mg once a day. If there is not adequate improvement after several weeks, the dose may be increased to a maximum of 450 mg once a day in the morning.

Extended release tablets (Aplenzin):

Initial dose: 174 mg orally once a day in the morning (equivalent to 150 mg bupropion HCl).

Maintenance dose: After at least 4 days, the dose may be increased to 348 mg once a day (equivalent to 300 mg bupropion HCl). If there is not adequate improvement after several weeks, the dose may be increased to a maximum of 522 mg once a day in the morning (equivalent to 450 mg bupropion HCl).

Usual Adult Dose for Smoking Cessation

Initial Dose: 150 mg orally once a day.

Maintenance: Based on clinical response, this dosage may be increased to 300 mg/day, given as 150 mg twice a day, no sooner than 3 days after beginning therapy.

Usual Adult Dose for Seasonal Affective Disorder

Initiate treatment for seasonal affective disorder in the autumn prior to onset of symptoms.

Wellbutrin XL (R):

Initial: 150 mg orally once a day in the morning

Titration: If tolerated, after 7 days dose may be increased to maximum dose of 300 mg once a day administered in the morning. Patients who are unable to tolerate this increase in dose should be reduced back to 150 mg orally once a day.

Aplenzin (R):

Initial: 174 mg once daily (equivalent to 150 mg bupropion) in the morning

Titration: If tolerated, after 7 days dose may be increased to 348 mg once daily (equivalent to 300 mg bupropion) in the morning through the winter season.

Usual Geriatric Dose for Depression

Initial dose: 75 mg orally twice a day.

Maintenance dose: 75 mg orally 3 times a day.

Maximum doses:

Immediate Release: 150 mg orally 3 times a day.

Sustained Release: 400 mg given as 200 mg twice a day.

Usual Pediatric Dose for Attention Deficit Disorder

Immediate release tablets:

6 to 18 years:

20 to 30 kg: 50 to 150 mg/day in 2 divided doses (investigational).

31 to 40 kg: 75 to 200 mg/day in 2 divided doses (investigational).

Greater than 40 kg: 100 to 250 mg/day in 2 divided doses (investigational).

Extended release tablets:

Less than 11 years: Safety and effectiveness have not been established.

11 to 18 years: 150 to 300 mg/day in 2 divided doses (investigational).

Usual Pediatric Dose for Smoking Cessation

14 years of age or older and greater than 40.5 Kg:

Hydrochloride salt: 150 mg orally twice a day of sustained release for seven weeks with cessation counselling.

Disclaimer: Information and data on Bupropion Hydrochloride (generic Wellbutrin XL®) found on this website is for informational purposes only. This information does not constitute legal advice and it is recommended to first check all information with your medical practitioner.

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