Brand Name: Nuvigil®
Armodafinil is a medication that promotes wakefulness.
Armodafinil is used to treat excessive sleepiness caused by sleep apnea, narcolepsy, or shift work sleep disorder.
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Other Known Brand Names for Nuvigil
- Armod (Emcure Pharmaceuticals Ltd.)
- Artvigil (HAB Pharmaceuticals & Research Ltd.)
- Biryth (Emcure Pharmaceuticals Ltd.)
- Nuvigil (Cephalon)
- Waklert (Sun Pharmaceutical Industries Ltd.)
Take armodafinil exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
Armodafinil is usually given for up to 12 weeks. Follow your doctor's instructions.
Armodafinil is usually taken each morning to prevent daytime sleepiness, or 1 hour before the start of a work shift to treat work-time sleep disorders.
If you are taking armodafinil to treat sleepiness caused by obstructive sleep apnea, you may also be treated with a continuous positive airway pressure (CPAP) machine. This machine is an air pump connected to mask that gently blows pressurized air into your nose while you sleep. The pump does not breathe for you, but the gentle force of air helps keep your airway open to prevent obstruction.
Do not stop using your CPAP machine during sleep unless your doctor tells you to. The combination of treatment with CPAP and armodafinil may be necessary to best treat your condition.
Armodafinil will not cure obstructive sleep apnea or treat its underlying causes. Follow your doctor's instructions about all your other treatments for this disorder.
Taking this medication does not take the place of getting enough sleep. Talk with your doctor if you continue to have excessive sleepiness even while taking armodafinil.
Store armodafinil at room temperature away from moisture and heat.
Obstructive Sleep Apnea (OSA) and Narcolepsy
The recommended dose of armodafinil for patients with OSA or narcolepsy is 150 mg or 250 mg given as a single dose in the morning. In patients with OSA, doses up to 250 mg/day, given as a single dose, have been well tolerated, but there is no consistent evidence that this dose confers additional benefit beyond that of the 150 mg/day dose.
Shift Work Sleep Disorder (SWD)
The recommended dose of armodafinil for patients with SWD is 150 mg given daily approximately 1 hour prior to the start of their work shift.
Dosage adjustment should be considered for concomitant medications that are substrates for CYP3A4/5, such as steroidal contraceptives, triazolam, and cyclosporine.
Drugs that are largely eliminated via CYP2C19 metabolism, such as diazepam, propranolol, and phenytoin may have prolonged elimination upon coadministration with armodafinil and may require dosage reduction and monitoring for toxicity.
In patients with severe hepatic impairment, armodafinil should be administered at a reduced dose.
There is inadequate information to determine safety and efficacy of dosing in patients with severe renal impairment.
In elderly patients, elimination of armodafinil and its metabolites may be reduced as a consequence of aging. Therefore, consideration should be given to the use of lower doses in this population.
Disclaimer: Information and data on Armodafinil (generic Nuvigil®) found on this website is for informational purposes only. This information does not constitute legal advice and it is recommended to first check all information with your medical practitioner.