Brand Name: Accutane®
Isotretinoin is a form of vitamin A. It reduces the amount of oil released by oil glands in your skin, and helps your skin renew itself more quickly.
Isotretinoin is used to treat severe nodular acne. It is usually given after other acne medicines or antibiotics have been tried without successful treatment of symptoms.
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Other Known Brand Names for Accutane
- Accutane (Hoffmann-La Roche Ltd.)
- Acno (Ajanta Pharma Limited)
- Acnomor (Centurion Laboratories)
- Acutret (IPCA Laboratories Ltd.)
- Aczit (Canixa Life Sciences Pvt. Ltd.)
- Amnesteem (Mylan Pharmaceuticals Inc)
- Claravis (Barr Laboratories Inc.)
- Isac (Systopic Laboratories Ltd.)
- Isobest (Gracewell (div. Glenmark Pharma))
- Isopex (Apex Laboratories Limited)
- Isopil (Glowderma Lab Pvt. Ltd.)
- Isotane (Pacific Pharmaceuticals Ltd.)
- Isotec (Searle (India) Ltd.)
- Isotret (Liva Pharmaceuticals Ltd.)
- Isotroin (Cipla Limited)
- Ocotret (Ochoa Laboratories Ltd.)
- Oraret (Palsons Drugs & Chemical Industries)
- Roaccutane (Hoffmann-La Roche Ltd.)
- Sotret (Ranbaxy Laboratories Ltd.)
- Tretiva (Intas Pharmaceuticals Pvt. Ltd.)
- Tufacne (Piramal Healthcare Ltd.)
Take Isotretinoin exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Each prescription of Isotretinoin must be filled within 7 days of the date it was prescribed by your doctor. You will receive no more than a 30-day supply of Isotretinoin at one time.
Always take Isotretinoin with a full glass of water to prevent the capsule from melting in your esophagus (food pipe), causing irritation. Do not chew or suck on the capsule. Swallow it as quickly as possible. Take Isotretinoin with food or milk. Take this medication for the entire length of time prescribed by your doctor. Your acne may seem to get worse at first, but should then begin to improve.
To be sure this medication is not causing harmful effects, your blood may need to be tested often. Your liver function may also need to be tested. Visit your doctor regularly.
Never share this medicine with another person, even if they have the same symptoms you have. Store Isotretinoin at room temperature away from moisture, heat, and light.
Isotretinoin should be administered with a meal.
The recommended dosage range for Isotretinoin is 0.5 to 1.0 mg/kg/day given in two divided doses with food for 15 to 20 weeks. In studies comparing 0.1, 0.5, and 1.0 mg/kg/day,8 it was found that all dosages provided initial clearing of disease, but there was a greater need for retreatment with the lower dosages. During treatment, the dose may be adjusted according to response of the disease and/or the appearance of clinical side effects ? some of which may be dose related. Adult patients whose disease is very severe with scarring or is primarily manifested on the trunk may require dose adjustments up to 2.0 mg/kg/day, as tolerated. Failure to take Isotretinoin with food will significantly decrease absorption. Before upward dose adjustments are made, the patients should be questioned about their compliance with food instructions.
The safety of once daily dosing with Isotretinoin has not been established. Once daily dosing is not recommended.
If the total nodule count has been reduced by more than 70% prior to completing 15 to 20 weeks of treatment, the drug may be discontinued. After a period of 2 months or more off therapy, and if warranted by persistent or recurring severe nodular acne, a second course of therapy may be initiated. The optimal interval before retreatment has not been defined for patients who have not completed skeletal growth. Long-term use of Isotretinoin, even in low doses, has not been studied, and is not recommended. It is important that Isotretinoin be given at the recommended doses for no longer than the recommended duration. The effect of long-term use of Isotretinoin on bone loss is unknown.
Contraceptive measures must be followed for any subsequent course of therapy.
Disclaimer: Information and data on Isotretinoin (generic Accutane®) found on this website is for informational purposes only. This information does not constitute legal advice and it is recommended to first check all information with your medical practitioner.